Mortality of Parkinson's disease by Hoehn–Yahr stage from community‐based and clinic series [Keelung Community‐based Integrated Screening (KCIS) no. 17)]
Identifieur interne : 000A26 ( Main/Exploration ); précédent : 000A25; suivant : 000A27Mortality of Parkinson's disease by Hoehn–Yahr stage from community‐based and clinic series [Keelung Community‐based Integrated Screening (KCIS) no. 17)]
Auteurs : Horng-Huei Liou [Taïwan] ; Chia-Yun Wu ; Yueh-Hsia Chiu ; Amy Ming-Fang Yen ; Rong-Chi Chen [Taïwan] ; Ta-Fu Chen ; Chih-Chuan Chen [Taïwan] ; Yuarn-Chung Hwang [Taïwan] ; Ying-Rong Wen [Taïwan] ; Tony Hsiu-Hsi Chen [Taïwan]Source :
- Journal of Evaluation in Clinical Practice [ 1356-1294 ] ; 2009-08.
English descriptors
Abstract
Purpose We aimed to quantify the mortality reduction by which the early detection of Parkinson's disease (PD) within a community‐based study could reduce the number of advanced cases. Methods Data used in this study were derived from two community‐based surveys and from a clinical series of PD cases identified from a medical centre. The cumulative survival by Hoehn–Yahr (H–Y) scale was estimated and the mortality reduction derived from a community‐based survey was predicted. Results A total of 117 PD patients were detected through two community‐based approaches. By comparing the H–Y stage distribution of screen‐detected cases with those from the clinical series, a 22.5% excess in the number of early PD (H–Y stage I and stage II) were identified with screening. The risk ratios of being H–Y stage III or severe for community‐based detected cases versus clinical series were 0.49 (95% confidence interval: 0.30–0.78). The total death rate adjusted by H–Y stage distribution was 21% and 28% for cases from community and clinical series, respectively. Conclusions The present study revealed that early detection of PD through a community‐based survey may reduce 51% incidence of stage III or more severe PD at diagnosis, leading to a 25% reduction in mortality.
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DOI: 10.1111/j.1365-2753.2008.01041.x
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U" uniqKey="Chen T" first="Ta-Fu" last="Chen">Ta-Fu Chen</name></author><author><name sortKey="Chen, Chih Huan" sort="Chen, Chih Huan" uniqKey="Chen C" first="Chih-Chuan" last="Chen">Chih-Chuan Chen</name></author><author><name sortKey="Hwang, Yuarn Hung" sort="Hwang, Yuarn Hung" uniqKey="Hwang Y" first="Yuarn-Chung" last="Hwang">Yuarn-Chung Hwang</name></author><author><name sortKey="Wen, Ying Ong" sort="Wen, Ying Ong" uniqKey="Wen Y" first="Ying-Rong" last="Wen">Ying-Rong Wen</name></author><author><name sortKey="Chen, Tony Hsiu Si" sort="Chen, Tony Hsiu Si" uniqKey="Chen T" first="Tony Hsiu-Hsi" last="Chen">Tony Hsiu-Hsi Chen</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:79036379BCBB1548638DEF2796568A3FE6EEB533</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1111/j.1365-2753.2008.01041.x</idno><idno type="url">https://api.istex.fr/document/79036379BCBB1548638DEF2796568A3FE6EEB533/fulltext/pdf</idno><idno 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first="Ta-Fu" last="Chen">Ta-Fu Chen</name><affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Chen, Chih Huan" sort="Chen, Chih Huan" uniqKey="Chen C" first="Chih-Chuan" last="Chen">Chih-Chuan Chen</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Attending Physician, Department of Neurology, National Taiwan University Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Hwang, Yuarn Hung" sort="Hwang, Yuarn Hung" uniqKey="Hwang Y" first="Yuarn-Chung" last="Hwang">Yuarn-Chung Hwang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Attending Physician, Department of Neurology, Keelung Hospital, Department of Health, Executive Yuan</wicri:regionArea><wicri:noRegion>Executive Yuan</wicri:noRegion></affiliation></author><author><name sortKey="Wen, Ying Ong" sort="Wen, Ying Ong" uniqKey="Wen Y" first="Ying-Rong" last="Wen">Ying-Rong Wen</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Attending Physician, Department of Neurology, Far Eastern Polyclinic, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Tony Hsiu Si" sort="Chen, Tony Hsiu Si" uniqKey="Chen T" first="Tony Hsiu-Hsi" last="Chen">Tony Hsiu-Hsi Chen</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Professor, Division of Biostatistics, Graduate Institute of Epidemiology, College of Public Health, National Taiwan University, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Evaluation in Clinical Practice</title><idno type="ISSN">1356-1294</idno><idno type="eISSN">1365-2753</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, 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study could reduce the number of advanced cases. Methods Data used in this study were derived from two community‐based surveys and from a clinical series of PD cases identified from a medical centre. The cumulative survival by Hoehn–Yahr (H–Y) scale was estimated and the mortality reduction derived from a community‐based survey was predicted. Results A total of 117 PD patients were detected through two community‐based approaches. By comparing the H–Y stage distribution of screen‐detected cases with those from the clinical series, a 22.5% excess in the number of early PD (H–Y stage I and stage II) were identified with screening. The risk ratios of being H–Y stage III or severe for community‐based detected cases versus clinical series were 0.49 (95% confidence interval: 0.30–0.78). The total death rate adjusted by H–Y stage distribution was 21% and 28% for cases from community and clinical series, respectively. Conclusions The present study revealed that early detection of PD through a community‐based survey may reduce 51% incidence of stage III or more severe PD at diagnosis, leading to a 25% reduction in mortality.</div></front></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><noCountry><name sortKey="Chen, Ta U" sort="Chen, Ta U" uniqKey="Chen T" first="Ta-Fu" last="Chen">Ta-Fu Chen</name><name sortKey="Chiu, Yueh Sia" sort="Chiu, Yueh Sia" uniqKey="Chiu Y" first="Yueh-Hsia" last="Chiu">Yueh-Hsia Chiu</name><name sortKey="Wu, Chia Un" sort="Wu, Chia Un" uniqKey="Wu C" first="Chia-Yun" last="Wu">Chia-Yun Wu</name><name sortKey="Yen, Amy Ming Ang" sort="Yen, Amy Ming Ang" uniqKey="Yen A" first="Amy Ming-Fang" last="Yen">Amy Ming-Fang Yen</name></noCountry><country name="Taïwan"><noRegion><name sortKey="Liou, Horng Uei" sort="Liou, Horng Uei" uniqKey="Liou H" first="Horng-Huei" last="Liou">Horng-Huei Liou</name></noRegion><name sortKey="Chen, Chih Huan" sort="Chen, Chih Huan" uniqKey="Chen C" first="Chih-Chuan" last="Chen">Chih-Chuan Chen</name><name sortKey="Chen, Rong Hi" sort="Chen, Rong Hi" uniqKey="Chen R" first="Rong-Chi" last="Chen">Rong-Chi Chen</name><name sortKey="Chen, Tony Hsiu Si" sort="Chen, Tony Hsiu Si" uniqKey="Chen T" first="Tony Hsiu-Hsi" last="Chen">Tony Hsiu-Hsi Chen</name><name sortKey="Hwang, Yuarn Hung" sort="Hwang, Yuarn Hung" uniqKey="Hwang Y" first="Yuarn-Chung" last="Hwang">Yuarn-Chung Hwang</name><name sortKey="Wen, Ying Ong" sort="Wen, Ying Ong" uniqKey="Wen Y" first="Ying-Rong" last="Wen">Ying-Rong Wen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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